ObjectivesThis study examines the impact of extreme temperatures on hospital utilization and public health insurance program spending in a country with no universal health coverage.MethodsUsing nationwide U.S.county-level panel data and a fixed effects model, we estimate the impact of annual variations in the number of hot and cold days on hospital
Finite Fracture Mechanics Assessment in Moderate and Large Scale Yielding Regimes
The coupled Finite Fracture Mechanics (FFM) criteria are applied to investigate the ductile failure initiation at blunt U-notched and V-notched plates under mode I loading conditions.The FFM approaches are based on the simultaneous fulfillment of kupari paistinpannu the energy balance and a stress requirement, and they involve two material properti
Engaging Primary Care Physicians to Refer Patients to Home-Based Palliative Is Challenging and Complicated
Background: Before the Affordable Care Act (ACA), the financing landscape for fee-for-service health care lacked broad structure and incentives to provide palliative care outside hospitals.Since the ACA, several payers have taken the opportunity to offer home-based palliative care (HBPC) to their members.Objective: To evaluate the impact of outreac
Fermitins, the orthologs of mammalian Kindlins, regulate the development of a functional cardiac syncytium in Drosophila melanogaster.
The vertebrate Kindlins are an evolutionarily conserved family of proteins critical for integrin signalling and cell adhesion.Kindlin-2 (KIND2) is associated with intercalated discs in mice, suggesting a role in cardiac syncytium development; however, deficiency of Kind2 leads to embryonic lethality.Morpholino knock-down of Kind2 in zebrafish has a